The First Common Cold Sore Susceptibility Gene
نویسندگان
چکیده
منابع مشابه
The first common cold sore susceptibility gene.
The outcome of any interaction between a virus and host is determined by genetic and environmental factors and is manifest as either susceptibility to or chronicity of infection or severity of disease [1]. This interplay between host genetics and viral strain genomic sequence has been well defined in murine models of different viral infections, such as murine cytomegalovirus, retroviruses (Frie...
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BACKGROUND Herpes simplex virus type 1 (HSV-1) infects >70% of the United States population. We identified a 3-megabase region on human chromosome 21 containing 6 candidate genes associated with herpes simplex labialis (HSL, "cold sores"). METHODS We conducted single nucleotide polymorphism (SNP) scans of the chromosome 21 region to define which of 6 possible candidate genes were associated w...
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There is considerable evidence that social relationships can influence health, but only limited evidence on the health effects of the personality characteristics that are thought to mold people's social lives. We asked whether sociability predicts resistance to infectious disease and whether this relationship is attributable to the quality and quantity of social interactions and relationships. ...
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Herpes simplex virus is a widespread disease affecting about one-third of the world’s population. Many individuals suffer from its painful and debilitating manifestations, which greatly impact daily living and can lower one’s self-esteem and confidence. It is therefore vital to understand this disease process including its acquisition, replication, transmission, clinical manifestations, diagnos...
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ژورنال
عنوان ژورنال: Journal of Infectious Diseases
سال: 2011
ISSN: 0022-1899,1537-6613
DOI: 10.1093/infdis/jir635